What Top Biohackers Look for in a Mattress — and How NadaUp Delivers

In the evolving world of human optimization, elite performers, wellness influencers, and longevity experts are turning their attention to the foundational pillar of health: sleep. No longer seen as a passive state of rest, sleep has been redefined by biohackers as an active biological process that deeply influences physical recovery, mental clarity, emotional regulation, and even cellular regeneration. As pioneers like Bryan Johnson, Andrew Huberman, and Ben Greenfield increasingly emphasize sleep in their protocols, it becomes clear that your mattress isn’t just a comfort item — it’s a critical health tool.

At NadaUp, we’ve embraced this philosophy. Our medically approved, scientifically engineered mattress isn’t just designed for luxury. It’s built to deliver quantifiable wellness outcomes. Here’s a deeper look at what the top minds in health optimization look for in a mattress — and how NadaUp meets and exceeds those expectations.

Pressure Relief and Musculoskeletal Support

Bryan Johnson has frequently discussed mechanical stress on the body as a contributor to chronic inflammation. During sleep, pressure points on the hips, shoulders, and spine can lead to micro-injuries that interfere with true recovery.

NadaUp mattresses are crafted using Mammoth Medical™ Grade Foam, a material originally designed for medical and therapeutic use. Our clinical tests show 60% better pressure relief, allowing joints and muscles to relax without tension. This not only improves comfort but also reduces cortisol accumulation associated with pain and discomfort during sleep.

Cooling and Thermal Regulation

In neuroscience circles, Dr. Andrew Huberman has repeatedly emphasized the importance of thermoregulation for sleep quality. A cooler sleep environment enhances the body’s natural circadian rhythm, allowing melatonin to rise and core body temperature to fall — both essential for entering deep, slow-wave sleep.

NadaUp integrates breathable, temperature-responsive materials that enable 69% better cooling and sleep comfort. Unlike foam mattresses that trap heat, our technology allows for airflow and thermal balance, a feature well-aligned with optimal sleep research.

Circadian Alignment and Hormonal Flow

Sleep is a hormonal symphony. From melatonin and cortisol to dopamine and serotonin, the brain releases a sequence of chemicals that govern the body’s ability to rest and repair.

NadaUp supports this biological rhythm through its alignment and adaptability. With medical certifications from MHRA and compliance with NICE guidelines, our mattress promotes proper spinal posture, encouraging a parasympathetic nervous system response — the "rest and digest" state critical for hormone regulation.

Our clients report falling asleep 29% faster and experiencing 7% better sleep efficiency, aligning perfectly with the biohacker goal of deeper, faster, and longer sleep.

Quantifiable Performance Metrics

The most respected biohackers track everything: heart rate variability (HRV), respiratory rate, skin conductivity, and deep sleep percentages. In one of our case studies, a client who used NadaUp in conjunction with a fitness wearable saw a 9.36% increase in HRV, a 24.16% decrease in stress levels, and a 9.87% drop in resting heart rate over 6 months.

These aren’t soft claims. NadaUp is data-driven, just like Bryan Johnson’s Blueprint protocol. We encourage users to track their sleep metrics before and after switching to NadaUp to witness a measurable transformation.

Certified Health and Wellness Integration

NadaUp is not just another wellness brand with clever marketing. We have real credentials:

  • MHRA (Medicines and Healthcare Products Regulatory Agency): Approved for safe and effective sleep support

  • ACPOHE (Association of Chartered Physiotherapists in Occupational Health and Ergonomics): Endorsed for improving posture and reducing sleep-related pain

  • NICE (National Institute for Health and Care Excellence): Recognized for aligning with national sleep quality standards

  • CSP (Chartered Society of Physiotherapy): Validated for supporting spinal alignment and back health

A Sleep Platform for the Biohacker Generation

In an age where supplements, blue light blockers, infrared saunas, and red light therapy dominate the longevity landscape, your mattress should not be the weakest link in your health stack.

NadaUp offers:

  • Medical-grade support

  • Clinically validated sleep improvements

  • Technological integration for bio-tracking

  • Peace of mind, backed by regulatory approvals

For the modern biohacker or sleep enthusiast, NadaUp isn’t a luxury — it’s a necessity.

Upgrade Your Sleep Stack

Biohackers optimize every variable in their control — nutrition, training, stress, focus, and tech. But without regenerative, quality sleep, none of these variables reach their full potential.

NadaUp mattresses are the silent partner in that journey. They don’t beep or buzz. They don’t need a charge. But they transform your night, so you can own your day.

If Bryan Johnson or Andrew Huberman were to evaluate a mattress for measurable impact on human performance  — NadaUp would be on that list.

Sleep well. Live longer. Start with NadaUp.

[Visit www.nadaup.com to learn more.]